Diagnostic Testing (Labwork and Other Testing)
Thyroid hormones play a very important role in maintaining our overall health and wellness.
Subclinical Hypothyroidism when untreated increases the risk of Atherosclerosis and Heart attacks (Myocardial Infarction), High Cholesterol, Overweight, Metabolic Syndrome and Dementia.
Research has shown that Females 55 years and older with Subclinical Hypothyroidism have a greater than two fold risk of Heart attacks.
Most Physicians including Endocrinologists, measure TSH alone to make a diagnosis of Hypothyroidism. TSH is a hormone that is released by the Pituitary gland in response to serum levels of T4 & T3, but not in response to cellular levels of T3. Therefore, measuring TSH alone is an unreliable way of diagnosing Hypothyroidism.
A comprehensive thorough Hormone blood work panel can help Identify Low Thyroid levels and a possible hormone imbalance.
A comprehensive Thyroid panel should include:
- Free T4
- Free T3
- Anti-TPO antibodies
- Serum Cortisol (When Adrenal Fatigue is suspected)
- Reverse T3 (rT3) (Elevated when Stress is high)
- Vitamin B12, Vitamin D, Vitamin A
- AntiThyroglobulin antibodies*
- TRH stimulation test*
- 24 Hour Urinary T3* (*When diagnosis is unclear)
TSH: is the most commonly used screening test to diagnostic test for both Hyperthyroidism and Hypothyroidism. It is best to use it along with Free T4 and Free T3.
The AACE (American Association of Clinical Endocrinologists) has decreased the upper limit reference range of TSH to 3.0. The National Academy of Biochemical Scientists recommends a TSH of 2.5 as the upper limit of normal.
Anti-TPO antibodies: Elevated levels are seen in Hashimoto’s (Auto-Immune Thyroiditis).
Anti-Thyroglobulin (TG) antibodies: TG is the protein present in the Colloid. It is an Ideal tumor marker for Thyroid cancer and can help differentiate Benign (non-cancerous) from Malignant (Cancer). It is seen in 35% to 60% of patients with Hashimoto’s (Autoimmune hypothyroidism), 15% to 30% of patients with Graves’ disease & in 3% of general population.
Thyroid Uptake scan / Radioactive Iodine uptake (RAIU): A small amount of Radioactive Iodine (RAI) is injected into the vein and using a special camera, the amount of RAI uptake by the Thyroid gland is measured. This test measures thyroid function as well as help differentiate between Cold nodules (Low activity) vs Hot nodules (High activity).
- High RAI Uptake is seen in Hyperthyroidism, Iodine deficiency, Hashimoto’s disease
- Low RAI Uptake is seen in Primary Hypothyroidism, Subacute Thyroiditis, Excessive Iodine, Amiodarone
- Differentiating the types of Nodules: Hot nodule (High activity: Benign), Cold nodule (Low activity: may suggest Cancer)
Thyroid Ultrasound: Non-Invasive method of detecting the texture of the Thyroid gland, small nodules in the Thyroid. It can also be done to perform an Ultrasound guided biopsy or FNAC.
Fine Needle Aspiration Biopsy: First step in the evaluation of a Thyroid nodule.
This website is for informational purposes only and does not offer medical advice. Some of the statements have not been evaluated by the Food and Drug Administration. The products and services discussed are not intended to diagnose, cure, or prevent any disease. All the services offered at Ageless Integrated Medicine can be prescribed by our Physician, which will include a thorough review of your Medical History, Physical Examination and possible Blood work Laboratory analysis. After such a thorough review, our Physician will determine if you are an appropriate candidate for the treatment sought based on your Individual Medical History, current health status and Laboratory results.